Innovative Science,
Designed for Women.
Meet The Science Behind P.Happi®: Powered by innovation and guided by research, P.Happi® is the first solution designed to actively defend the microbiome – proven by science, created for women. Explore the science behind our pioneering work and discover how it works with your body.
Innovative Science. Designed for Women.
Meet The Science Behind P.Happi® - The New Solution That Gently Supports Your Microbiome Naturally.
Powered by innovation and guided by research, P.Happi® is the first solution designed to actively defend the microbiome – proven by science, created for women. Explore the science behind our pioneering work and discover how it works with your body.
A New Ingredient
The First Of Its Kind
Bdellovibrio bacteriovorus (B.Y.M.® 1405), is a unique natural ingredient. It is a good bacterium in itself that targets and breaks down Gram-negative bacteria such as UTI causing E. coli, protecting and allowing the good and Gram-positive lactobacilli bacteria in the urovaginal microbiome to thrive.
Swipe To See How B.Y.M.® 1405 Targets & Breaks Down Gram-Negative Bacteria
B.Y.M.® 1405 Targets & Breaks Down Gram-Negative Bacteria
How is this different to antibiotics?
Founded By Scientist & Fellow UTI Sufferer
Dr Chiara Board, PhD (Imperial College London), created P.Happi® after years of battling recurrent UTIs herself. Frustrated by quick fixes that didn’t last, she used her expertise in Synthetic Biology and Bioengineering to develop a first-of-its-kind Bdellovibrio-based serum.
Her mission? To empower women with effective, science-backed solutions that work with your body – not against it — supported by rigorous research from our lab in London.
My goal is to empower women with solutions that are effective, accessible, and in harmony with their body.
DR CHIARA BOARD, CEO + FOUNDER
Why This New Approach?
Applied topically to the vulva and perineum
Fast activity on contact. Hassle-free application
Shields from harmful bacteria before they enter the intimate area
Directly applied where needed: Does not need to travel through the digestive system
Targets a broad range of Gram-negative bacteria
Dual action technology: Microbiome protecting + moisturising
Our Lab Studies Show
B.Y.M.® 1405 has proven to eliminate 99.98% of E.coli within 24 hrs to undetectable levels
Our Lab Studies Show
B.Y.M.® 1405 has proven to eliminate 99.98% of E.coli within 24 hrs to undetectable levels
Science You Can See
Swipe right to see how B.Y.M.® 1405 in P.Happi® helps to stop bacteria, naturally without antibiotics
See a plate full of E.coli (purple dots) before applying B.Y.M.® 1405
24 hrs later, after applying B.Y.M.® 1405 the E. coli colonies have massively reduced (fewer purple dots)
From Lab to Life: Proven Results With B.Y.M.®
Most brands stop at ingredient-level claims. We don’t. We do tests, both with our ingredient (B.Y.M.® 1405) and with it as a complete serum formulation because concentration, combinations, and application methods can significantly influence real-world results.
6-Month In Vivo Microbiome Study:
Women Report Significant
Improvements In Intimate Health
Over 1,000 women applied to join the study. From these, 60 peri- and post-menopausal women were enrolled to track their symptoms and progress over a 6-month period.
Women reported a statistically significant reduction in symptoms just one week after starting the serum, with continued improvement over time. Self-reported significant benefits included:
Reduced urgency and frequency of urination
Less bladder discomfort and pressure
Improved comfort when emptying the bladder
Relief from vaginal or vulval dryness and itching
Reduced irritation or sensitivity
Fewer leaks or accidents
Fewer flare-ups or recurrences
We work with women of all life stages (Pre, Peri and Post Menopause) — and participants have consistently reported positive outcomes.
Impact on sexual wellbeing significantly improved during the 12 week period of serum use
Certified Microbiome-Friendly
P.Happi® has been clinically tested under the MyMicrobiome standard for vulvo-vaginal health and awarded an exceptional score qualifying it as officially "Microbiome-Friendly." This means it’s gentle, safe, and scientifically proven to support your intimate microbiome without causing imbalance — ideal for sensitive, unbalanced skin.
The test confirmed that the serum maintains a healthy balance of key bacteria (like Lactobacillus crispatus) and does not disturb the natural diversity or growth of protective microbes.
In vitro tests carried out by a third party where scientists exposed key vaginal microbes to the serum and observed their behaviour. They tested for microbial quality, the influence on natural healthy skin balance including its influence on bacterial diversity and growth behaviour of microbes. The result? No harm to beneficial bacteria, and no growth of harmful ones like E. coli or Staph. aureus.
A healthy intimate microbiome is your first line of defence against infections, irritation, and dryness. That’s why we formulated P.Happi to work with your body — not against it.
Validated microbiome-friendly not only in a lab, but on real vaginal samples
Twice daily application of a serum containing B.Y.M.® 1405 to the external genitalia for two weeks did not alter the absolute abundance of vaginal Lactobacillus species (normal protective flora) colonising in 41 women.
Certified suitable for sensitive skin
Patch testing has been carried out by ADSL labs who have certified P.Happi as non-irritating and suitable for sensitive skin.
Twice a Day Application Improves Efficacy
In a study on peri- and post-menopausal women, participants swabbed their external genitalia throughout a 24-hour period of normal serum application.
In the evening, before reapplying the serum, B.Y.M.® 1405 was not detected in 47% of the participants' samples.
Twice daily use of P.Happi® is up to 64% more effective at maintaining protective levels of B.Y.M.® 1405 compared to skipping a day.
We're Truly Science-Backed
P.Happi® is created by a team of scientists in our lab in London where we are working hard to push the boundaries of women’s intimate health research.
In collaboration with our credible partners, we continue to advance our technology through ongoing lab research (in vitro) and studies involving real women (in vivo).
Don't Wait To Protect Your Microbiome
Join the women already experiencing science-backed protection and care.